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-80°C Low Cost Freeze Dryer

Hawach’s -80°C low cost freeze dryer has four types: digital display; LCD display; electronic heating and LCD display; in-situ -80 °C, electronic heating and LCD display.

Description

-80°C mini freeze dryer machine, digital display

This -80°C mini freeze dryer machine is an option for -50°C vacuum freeze drying machine. Compared to the -50 series, the -80 series lyophilizer machine has lower condensation temperature — -80 degrees centigrade, and higher vacuum degree — <10Pa.

Technical parameters of -80°C mini freeze dryer machine

Model FD-80-A FD-80-B FD-80-C FD-80-D FD-80-E
Type Ordinary Gland Ordinary Hang
8-bottled
Gland Hang 8-bottled T-shelf multiple
24-bottled
Condensation temperature <-80℃
Vacuum Degree <10Pa
Drying Area (㎡) 0.12 0.07 0.12 0.07 ——-
Material Volume ( L) 1.2 0.7 1.2 0.7 ——-
Water-capture capability 3kg/24h
Tray size & quantity(pcs) Φ20cm×4 Φ20cm×3 Φ20cm×4 Φ20cm×3 ——-
Tray Spacing 7cm
Power Supply 220V/50Hz/850W
Size (cm) 49.2*54*80

-80°C laboratory lyophilizer, LCD display

An upgraded version of -56°C lab scale freeze dryer, Hawach’s -80°C laboratory lyophilizer has cold trap temperature lower than -80 degrees centigrade and is equipped with dual refrigerating systems.
Technical parameters of -80°C laboratory lyophilizer

LFD80-12 series

Model Unit LFD80-12A LFD80-12C LFD80-12B LFD80-12D
Specification Ordinary 8-bottled Gland Gland 8-bottled
Freeze-drying area 0.12 0.08
Cold trap Temperature < -80 (no-loading)
Vacuum degree Pa ≤ 5 (no-loading)
Water-capture capability kg/24h 3-4
Tray dimension cm φ20*4 φ18*3
Total Power w 950
Weight kg 41
Dimension cm 63×45×37
Bulk capacity
(thickness 1cm)
L 1.2 1.5 0.8 1.2
Vial loading number pcs Ф12mm*920
Ф16mm*480
Ф22mm*260
Ф12mm*560
Ф16mm*285
Ф22mm*165

LFD80-18 series

Model Unit LFD80-18A LFD80-18C LFD80-18B LFD80-18D
Specification Ordinary 8-bottled Gland Gland 8-bottled
Freeze-drying area 0.18/0.27 0.09
Cold trap Temperature < -80 (no-loading)
Vacuum degree Pa ≤ 5 (no-loading)
Water-capture capability kg/24h 6
Tray dimension cm φ24*4/6 φ20*3
Total Power w 2100
Weight kg 105
Dimension cm 63×58×97
Bulk capacity
(thickness 10mm)
L 1.8/2.7 2/3 1 1.2
Vial loading number pcs Ф12mm*1320
Ф16mm*740
Ф22mm*360
Ф12mm*690
Ф16mm*360
Ф22mm*195

-80°C pilot scale lyophilizer, electronic heating; LCD display

Hawach’s -80°C pilot scale lyophilizer is another choice for -60°C tray freeze dryer. Besides its lower condensation temp -80°C, this lyophilizer machine also has dual condensers.

Technical parameters of -80°C pilot scale lyophilizer

Model Unit LFD80EH-18A LFD80EH-18C LFD80EH-18B
Specification Ordinary 8-Bottled Gland
Freeze-drying area 0.18/0.27 0.09
Cold trap Temperature < -80
Vacuum degree Pa ≤ 5 (no-loading)
Water-capture capability kg/24h 6
Tray dimension cm φ24*4/6 φ20*3
Total Power w 2100
Weight kg 105
Dimension cm 63×58×97
Bulk capacity
(thickness 10mm)
L 1.8/2.7 2/3 1
Vial loading number pcs Ф12mm*1320
Ф16mm*740
Ф22mm*360
Ф12mm*690
Ф16mm*360
Ф22mm*195

-80°C in-situ industrial lyophilizer, electronic heating; LCD display

-80°C in-situ industrial lyophilizer also differs from its -55°C version regarding temperature and refrigeration system.

Technical parameters of -80°C in-situ industrial lyophilizer

Model # ILFD55EH-20A ILFD55EH-20B ILFD55EH-40A ILFD55EH-60A
Freeze Area(M2) 0.2 0.1 0.4 0.6
Lowest Temp.(C) -80
Vacuum (Pa) </=-5
Water Capture
(kg/24h)
4 6 10
Partition Temp. (C) -70 to +70
Power(kw) 2.3 2.85 4.5
Volume(L, 1cm) 2 1 4 6
Tray size&Qty (cm) 40*27*2 layer 40*27*1 layer 30*34*4 layer 30*34*6 layer
Tray Spacing(cm) 7 5
Bottle #(pcs) Ф12mm*1400
Ф16mm*768
Ф22mm*408
Ф12mm*700
Ф16mm*384
Ф22mm*208
Ф12mm*2592
Ф16mm*1440
Ф22mm*780
Ф12mm*3888
Ф16mm*2160
Ф22mm*1170
Weight(kg) 260 400
Dimension(cm) 65*67.5*135 65*67.5*150 70*85*140

Several parameters that should be paid attention to when purchasing a lyophilizer machine

low cost freeze dryer

1. Freeze-dried area
Users should determine how much freeze-drying area to use according to their own needs. Hawach’s ordinary -80°C mini freeze dryer machine, FD-80 -A has drying area of 0.12㎡. For example, for each batch of products that require lyophilization of 1.2 kg (liter) of liquid, use the material tray to load the material, each tray is loaded with 10㎜ thick, then the load area of the freeze-dried board layer can be calculated:
A (Area, ㎡) = V (Volume, m3) / H (Height, m) = 0.0012m3 / 0.01m = 0.12㎡
It is necessary to select a lyophilizer machine with a layer load area of 0.12㎡.

2. Cold trap temperature
Cold trap is a device to capture water in the freeze-drying process. Theoretically, the lower the temperature of the cold trap, the stronger the water-capturing ability. The temperature of the cold trap of the laboratory lyophilizer mainly has several grades such as about -45 ℃, about -60 ℃, and about -80 ℃. Freeze-drying with the first grade temperature is suitable for some products that are easy to freeze-dry; the second for most products, and the third for special products.

3. Cooling rate
The cooling rate reflects the cooling capacity of the refrigeration system. Under no-load conditions, the cold trap temperature should reach the minimum temperature specified in the index within 1 hour. For example, for a freeze dryer with a cold trap temperature ≤-80 ° C,
(Hawach’s low cost freeze dryer -80 series), the machine will start timing when the refrigeration is turned on, and the time for the cold trap temperature to reach -60 ° C shall not exceed 1 hour.

pilot scale lyophilizer

4. Temperature uniformity and flatness of the material shelf
Temperature uniformity and flatness of the shelf have a great influence on product quality uniformity. The temperature control of the shelf includes heater type and intermediate fluid type. And the latter is better regarding the two indicators. The cooling and heating are achieved through the circulation of the intermediate fluid in the fluid channel inside the shelf, so the temperature of the layer is uniform. The temperature control of the shelf of the bell-type lyophilizer machine (Hawach’s pilot scale lyophilizer -80 series, for example) is basically a heater, and the temperature consistency of the shelf is slightly worse. But in general, the temperature difference of the shelf for medicine should be controlled within ± 1.5 ℃, and the temperature difference within the plate should be ± l ℃.

5. Control system
The control system and functions of freeze dryers are different. For the laboratory lyophilizer, it is mainly used in the exploration of lyophilization process and a small amount of trial production. Therefore, the control system should be able to display and automatically record the parameters of the freeze-drying process in real time; able to set, modify and effectively execute the freeze-drying process program; have a USB interface for data collection and storage.

Certificate
Hawach Scientific Co., Ltd achieved ISO9001 certificate in the 2009 year and renew it in the 2015 year by TÜV Rheinland. All products are manufactured under ISO 9001 quality management system.

certificate
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